K.J. McDaniels scored 15 points and had 12 rebounds to lead Clemson to a 61-53 win over Wake Forest on Saturday.
The Tigers (13-4, 4-1 Atlantic Coast) are off to their best start in the ACC since winning their first five league games in 1997, the last time Clemson went to the Sweet 16.
The Tigers again relied on their nation-leading defense. Clemson has held every ACC opponent to 60 points or under this year.
Wake Forest (12-6, 2-3) shot just 36.2 percent (21-of-58), matching Clemson's field goal defense for the season exactly. The Tigers also came into the game allowing just 53.6 points a game.
Coron Williams led the Demon Deacons with 13 points.
Wake Forest is now 1-27 on the road in the ACC under fourth-year coach Jeff Bzdelik.