Horry County Fire Rescue is on scene of a wreck at Highway 410 and the Highway 9 Bypass in the Finklea community.
Highway Patrol says the wreck happened at 10:08 a.m.
Five people were taken to the hospital, according to Horry County Fire Rescue.
Traffic signals are down.
Highway 410 is closed. Highway 9 Bypass is closed to one each direction.