An overturned truck on U.S. 378 in Florence County is blocking the highway, according to South Carolina Department of Public Safety and South Carolina Highway Patrol.
This is east of Lake City near Stone Chapel Church.
Detours are in place, but drivers should avoid the area if possible.
Delays are expected for at least three hours, according to DPS officials.
The wreck involves injuries, according to South Carolina Highway Patrol. It happened around 5:40 a.m. Tuesday.