Traffic is back to normal on 501 following a wreck just after 7 a.m. Wednesday.
The wreck happened at East Cox Ferry Road and Highway 501.
South Carolina Highway Patrol is reporting injuries. There were at least two vehicles involved, a van and a sedan.
Conway Fire crews and Horry County Fire Rescue firefighters are on scene.
NewsChannel 15's Jack Lamson was on scene and saw two people pulled from the car by Conway Fire Rescue and Horry County Fire Rescue.
The crash is under investigation.