Two men were killed about 5 p.m. Tuesday in a crash at the intersection of New Market Road and West Old Camden Road near Hartsville.
Darlington County Coroner Todd Hardee says Dargan Glenn Brown, 22, of Hartsville, and Steven Damico, 62, of Hartsville were both pronounced dead at the scene.
Highway Patrol says Brown was a passenger in a car that ran a stop sign and hit the car being driven by Damico.
Brown was thrown from the car.
The driver of the car Brown was in was airlifted to the hospital. Her condition has not been released.
The SC Highway Patrol is investigating the wreck.