Police say the robber was wearing a costume mask, brown coat and a green hat.
They say he was driving a small dark car, possibly with North Carolina plates.
They ask that you call 843-915-5350 if you see the robber.
The same bank was robbed in December. Horry County police arrested the suspect in that case.
Tuesday's robbery was the third bank robbery in Horry County this month. The Crescent Bank in Garden City was robbed on June 3rd. And, the BB&T in Murrells Inlet was robbed on June 1st. Police are still looking for the suspects in those cases.