An end unit of a four-plex on Volterra Way in Belle Terre burned Friday afternoon.
Horry County Fire Rescue says lightning caused the fire at the vacant townhouse.
The fire started just before 5 pm.
Even after the fire was out, smoke poured out of the home and filled the sky.
There were more than a dozen emergency vehicles on scene and at least 20 firefighters.
First responders included units from Horry County Fire Rescue, Myrtle Beach Fire, and Conway Fire.