Two men robbed the Speedy Mart on West Lucas Street in Florence just after 6:15 p.m. Tuesday.
One of the men was armed with two guns and fired shots in the store during the robbery, according to Florence police.
Officers say no one was hurt.
The men left the store with an undisclosed amount of money.
If you have any information you're asked to call Florence police at (843) 665-3191 or CrimeStoppers at 1-888-CRIME-SC.